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LIAISON® EBV Diagnostic Solution

Diasorin offers four individual tests to aid in the diagnosis and staging of EBV infection.

By providing a full panel for the parallel determination of VCA IgG, EBNA IgG and EBV IgM levels, Diasorin enables efficient detection of EBV infection and an optimized discrimination of the  infection stage.

LIAISON® XL

LIAISON® EBV IgM

Chemiluminescence (CLIA) assay for the quantitative determination of specific IgM antibodies to Epstein-Barr viral capsid antigens (VCA) in human serum or plasma samples.

LIAISON® XL

LIAISON® VCA IgG

Chemiluminescence (CLIA) assay for the quantitative determination of specific IgG antibodies to Epstein-Barr viral capsid antigens (VCA) in human serum or plasma samples.

LIAISON® XL

LIAISON® EBNA IgG

Chemiluminescence (CLIA) assay for the quantitative determination of specific IgG antibodies to Epstein-Barr virus nuclear antigen (EBNA) in human serum or plasma samples.

LIAISON® XL / LIAISON® XS

LIAISON® EA IgG

Chemiluminescence (CLIA) assay for the quantitative determination of specific IgG antibodies to Epstein-Barr virus early antigen-diffuse [EA(D)] in human serum or plasma samples.

Indications for use

Diagnosis

Differential diagnosis and staging of the infection

Target patient

Adults and children

Use Area

General medicine, pediatric medicine, prenatal medicine

LIAISON® EBV Diagnostic Solution for the determination of Epstein Barr Virus - Diasorin

Background

Epstein-Barr Virus (EBV) is the causative agent of infectious mononucleosis.
The clinical diagnosis can be challenging because the symptoms are similar to other illnesses and serological testing is used to exclude other diseases and assess disease states. 
EBV  serological testing  measures IgG and IgM antibodies directed against different components of the virus.. Antigens from the Viral Capsid (VCA) are used to detect antibodies generally produced during the acute phase of the infection whereas the EBNA-1 protein is used to detect IgG produced during convalescence.
Quantitative assays and use of differential cut-off for the interpretation of EBNA IgG and EBV IgM results, provide clinicians a way to better discrimination among different phases of EBV infection.

How it works

Disease evolution

EBV Infection Evolution Graph - Diasorin

Results interpretation

VCA IgM
VCA IgG
EBNA IgG
EA IgG
Diagnosis

-

-

-

-

EBV negative

+

-

-

-

Early phase of acute infection

+

+

-

+/-

Acute primary infection

-

+

+

+/-

Past infection

Test for the diagnosis and detection of the stage of Epstein Barr virus infection

Why use LIAISON® EBV Diagnostic Solution

Full automated EBV test panel aiding in differential diagnosis and staging EBV infection

Quantitative assays

Full panel of quantitative assays.

Differential cut-off

The use of a differential cut-off for the interpretation of EBNA IgG and EBV IgM results, allows better discrimination among different phases of EBV infection.

To be used on

Designed for both specialty and routine tests, LIAISON® XL and LIAISON® XS immunoassay analyzers help your laboratory handle multiple patients and tests simultaneously. LIAISON® systems are trustworthy, intuitive and deliver automated continuous operation with minimal user intervention. The result is reduced turnaround time, optimal cost management and unmatched growth potential.

Fully Automated LIAISON® XL System - Diasorin

LIAISON® XL

Designed for large laboratories. Combine the benefits of high throughput and high sensitivity within a powerful and fully automated system that can seamlessly connect to facilitate Total Laboratory Automation. 

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Fully Automated LIAISON® XS System - Diasorin

LIAISON® XS

A fully automated, easy-to-use benchtop analyzer. Maximize productivity with optimal cost management, no daily maintenance, straightforward integration, and the same capabilities as Diasorin’s high-throughput analyzers. 

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More details about our diagnostic solutions

Login to Dialog for additional resources

Login to our repository for instructions for use and user manuals, assay information, protocols and much more.

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If you need any information about our products, contact our specialists. 

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