The use of some assays has become particularly important after implementation of screening programs in a number of countries to identify pregnant women at risk of materno-fetal infections caused by Toxoplasma, Parvovirus B19, Rubella, Cytomegalovirus and Herpes simplex viruses (the so-called ToRCH panel) and to monitor the outcome once one disease is recognized.
Infection with TORCH organisms frequently causes only mild maternal infection, but can result in serious consequences for the fetus. For this reason, the performance of serological tests is extremely important for accurate diagnosis and correct clinical management of patients. To improve serological diagnosis, measurement of IgG avidity has recently been introduced to stage the infection and calculate the risk to the fetus. The ability to distinguish between ongoing and past infection helps to avoid anxiety and unnecessary treatment in.
DiaSorin offers a complete ToRCH panel on the LIAISON® systems.