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LIAISON® Lyme Disease Diagnostic Solution

Lyme borreliosis is among the world’s fastest growing infectious diseases and one of the most difficult to diagnose. If left untreated, the multi-organ tick-borne infection can cause neuropathy, meningitis, cardiac conduction abnormalities, and arthritis. Diasorin is helping prevent these effects with easy, automated and cost-effective serology testing.

LIAISON® XL / LIAISON® XS

LIAISON® LymeDetect®

LIAISON® LymeDetect® is an innovative approach to EARLY Lyme disease diagnosis that combines assays measuring B cell humoral immunity, LIAISON® IgG and IgM CLIA assays, and T cell mediated immunity with the patented QuantiFERON® IGRA technology. This supports early diagnosis of Lyme disease  to support treatment of patients before severe illness develops.
 

LIAISON® XL / LIAISON® XS

LIAISON® Borrelia IgG

The LIAISON®Borrelia IgG assay uses chemiluminescence immunoassay (CLIA) technology for the quantitative determination of specific IgG antibodies to Borrelia burgdorferi sensu lato in human serum, plasma or cerebrospinal fluid (CSF) samples. The test runs on the LIAISON® analyzer family.

LIAISON® XL / LIAISON® XS

LIAISON® Borrelia IgM II

The LIAISON®Borrelia IgM II assay uses chemiluminescence immunoassay (CLIA) technology for the qualitative determination of specific IgM antibodies to Borrelia burgdorferi sensu lato in human serum or plasma samples. The test runs on the LIAISON® analyzer family. 

LIAISON® XL / LIAISON® XS

LIAISON® Borrelia IgM Quant

The LIAISON®Borrelia IgM II assay uses chemiluminescence immunoassay (CLIA) technology for the quantitative determination of specific IgM antibodies to Borrelia burgdorferi sensu lato in human serum, plasma or cerebrospinal fluid (CSF) samples. The test runs on the LIAISON® analyzer family.

Indications for use

Diagnosis

Suspected Lyme disease, even from an early stage

Target patient

Adults and children exposed to a potential tick bite

Use area

General medicine, public health 

Background

Accurate detection means better prognosis

Because the clinical manifestation of Lyme borreliosis can be similar to that of other diseases, and early treatment is crucial in preventing potentially serious health issues, the accurate and early detection of Borrelia infections is a fundamental diagnostic aid.

The LIAISON® Lyme Disease Diagnostic Solution ensures improved diagnostic sensitivity in all stages of a Lyme borreliosis infection – from the first days after a tick bite (LIAISON® LymeDetect®) to weeks, months and years (LIAISON®Borrelia burgdorferi IgG and LIAISON®Borrelia burgdorferi IgM).

How it works

LIAISON® LymeDetect® is an exclusive diagnostic solution that combines two specialty LIAISON® assays with the patented QuantiFERON® IGRA technology. A powerful and cost-effective answer to increased detection accuracy, the innovative closed-loop test delivers a clear diagnosis in as little as 24 hours.

3 tubes +
1 automated process =
100% clear result

01

No need for specialized staff

LIAISON® LymeDetect® runs on the LIAISON® XL and LIAISON® XS chemiluminescence analyzers in any laboratory setting. 

02

Fast, clear results for EARLY detection

LIAISON® LymeDetect® ensures results  days after contact with an infected tick in a comprehensive assay. Results are combined in a single qualitative assay -- delivering a clear diagnosis in as little as 24 hours.

03

High-quality, ready-to-use CLIA assay

Standardized results, automatic processing and an inclusive and traceable workflow ensures easy integration into any lab routine.

The LIAISON® Borrelia assays are based on recombinant proteins that allow reduction of cross-reactivity problems providing higher specificity in comparison with whole-cell lysate assays. 
The use of immunodominant Borrelia antigens have improved the diagnostic sensitivity in all stages of Lyme infection.

Increases accuracy and help solve diagnostic ambiguities

01

No need for specialized staff

LIAISON® Lyme disease solutions run on the LIAISON® XL and LIAISON® XS chemiluminescence analyzers in any laboratory setting. 

02

Fast, automated, reproducible results

LIAISON® Lyme serology solutions (IgG and IgM) ensure timely results just in a single-step process, the recombinant technologies and the careful manufacturing procedures assure result operator independent.

03

High-quality, ready-to-use CLIA assay

Standardized results, automatic processing and an inclusive and traceable workflow ensures easy integration into any lab routine and virtually eliminates the cumbersome hands-on and subjective reading of traditional Serologic sTTT methods.

LIAISON® diagnostic solution for the diagnosis of Lyme disease - Diasorin

Why use LIAISON® Lyme Disease Diagnostic Solution

The high diagnostic accuracy of our LIAISON® Lyme Disease Diagnostic Solution helps solve diagnostic ambiguities, mitigating the effect of external factors that can complicate serological findings.

Pioneering diagnostic innovation

Unlike cumbersome standard two-tiered testing (sTTT), LIAISON® LymeDetect® can respond to early detection needs and reduce untreated infections that often lead to serious multi-organ complications.

Best-in-class performance

LIAISON® LymeDetect® offers significant improvement in sensitivity vs classical standard two-tiered testing (sTTT) in the first 21 days of the infection, from 48.5% (sTTT) to 73.5% with LIAISON® LymeDetect®

Fast, clear results

LIAISON® LymeDetect® ensures timely results just days after contact with an infected tick with the added advantage of a single-step process. Results are combined in a single qualitative assay -- delivering a clear diagnosis in as little as 24 hours.

Effective diagnosis

The innovative combination (serology + IGRA technology) of our LIAISON® Lyme disease solution ensures effective diagnosis within weeks of contact with an infected tick, with concrete benefits for physicians, patients and laboratories.

Fully automated and traceable workflow

Easy integration into daily lab routines, the fully automated solution virtually eliminates the cumbersome hands-on and subjective reading of the current standard of care.

Pioneering, easy-to-use diagnostics

Diasorin’s intuitive, end-to-end process ensures improved turnaround time, optimal cost management and straightforward integration within any laboratory workflow; improving response time without increasing operational costs.

To be used on

Designed for both specialty and routine tests, LIAISON® XL and LIAISON® XS immunoassay analyzers help your laboratory handle multiple patients and tests simultaneously. LIAISON® systems are trustworthy, intuitive and deliver automated continuous operation with minimal user intervention. The result is reduced turnaround time, optimal cost management and unmatched growth potential.

Fully Automated LIAISON® XL System - Diasorin

LIAISON® XL

Designed for large laboratories. Fuse the benefits of high throughput and high sensitivity within a powerful and fully automated system that can seamlessly connect to facilitate Total Laboratory Automation. 

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Fully Automated LIAISON® XS System - Diasorin

LIAISON® XS

A fully automated, easy-to-use benchtop analyzer. Maximize productivity with optimal cost management, no daily maintenance, straightforward integration, and the same capabilities as Diasorin’s high-throughput analyzers. 

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More details about our diagnostic solutions

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